Low Dose Naltrexone (LDN) is an emerging therapy used to manage chronic conditions, including autoimmune diseases, neurological disorders, and inflammatory conditions. Originally developed for treating opioid addiction in high doses, naltrexone is now being used in significantly lower doses for its ability to modulate the immune system and reduce inflammation.

Low-Dose Naltrexone (LDN) is an innovative medication with potential benefits across a broad spectrum of health conditions. Unlike traditional medications that treat symptoms or lower your immune system, LDN works by addressing underlying imbalances in the body. It enhances the production of endorphins and enkephalins—powerful chemicals that reduce pain, fix the immune system, and promote anti-inflammatory effects.

LDN was first discovered in the 1980s by Dr. Bernard Bihari, who observed its effects at doses 10 to 100 times lower than standard naltrexone doses. Research and clinical experience have since expanded its use to manage conditions such as multiple sclerosis, rheumatoid arthritis, Crohn’s disease, fibromyalgia, chronic fatigue syndrome, and mental health disorders. Its ability to favorably influence the immune system, as well as endocrine functions like thyroid, adrenal, and sex hormone balance, positions it as a transformative therapy for many chronic conditions.